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The recent application of high throughput technologies to transcriptomics has changed our view of gene regulation and function. The discovery of extensive transcription of large RNA transcripts, termed long noncoding RNAs (lncRNAs), provide an important and new perspective on the centrality of RNA in gene regulation. LncRNAs are involved in various biological and cellular processes, such as genetic imprinting, chromatin remodeling, gene regulation and embryonic development. LncRNAs have been implicated in several chronic diseases, such as cancers, and heart disease, etc. Various types of genomic data on lncRNAs are currently available, including sequences, secondary/tertiary structures, transcriptome data, and their interactions with related proteins or genes. The key challenge is how to integrate data from myriad sources to determine the functions and the regulatory mechanism of these ubiquitous lncRNAs.
Research topics
The potential topics include, but not limited to the following:
ncRNA detection and biomarker discovery
CLIP-Seq and RIP-Seq data analysis
Prediction of physical binding between lncRNA and DNA, RNA and protein.
Understanding the competition between lncRNA, miRNA and mRNA
Studying methylation regulating lncRNA functions
Function Prediction for lncRNAs
Deep learning approaches to lncRNA/RNA binding protein prediction
Computational approaches to analyzing lncRNA
lncRNA 3D secondary structures
lncRNA-protein interactions
lncRNA in epigenetic regulation
lncRNA associated diseases networks
lncRNAs in plant genomics
lncRNAs in phenotype-genotype problems
CRISPR/Cas9 and Genome editing in lncRNAs
We invite you to submit papers with unpublished, original research describing recent advances on the areas related to this workshop. All papers will undergo peer review by the conference program committee. All papers accepted will be included in the Workshop Proceedings published by the IEEE Computer Society Press and will be available at the workshops. Authors of selected papers will be invited to extend their papers for submission to special issues in prestigious Journals.
Travel Support
Funds are available for limited travel fellowships to support students and researchers from underrepresented minority groups.
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