Dear Colleagues, Optical fiber technology is an interesting sensing methodology that has been explored in diverse application fields, including medicine and biomedical applications. It has been used to monitor important physiological parameters such as heart rate, arterial pulse waveform, and oximetry; to detect cancer biomarkers; and to characterize new medical materials; among several others. For all this, fiber-optic sensors for biomedical applications is a very active research area, where challenges concerning the miniaturization, sensitivity, selectivity, applicability, accuracy, and biocompatibility need to be thoroughly addressed. This Special Issue will focus on the current state-of-the-art of optical fiber sensors for biomedicine, covering recent technological improvements in new devices/sensors and emerging applications. Both original research papers and review articles describing the current state-of-the-art in this research field are welcome. We hope that this SI will provide you with an overview of the present status and future outlook of the aforementioned topics. The manuscripts should cover, but are not limited to, the following topics: Optical fiber sensing of physiological parameters; New bio/chemical probes for medical applications; Optical integrated biomedical systems (lab-on-a-fiber); Optical fiber systems with microfluid integration; Wearable biomedical sensors; Non-invasive optical fiber devices; Optical fiber sensors in e-Health architectures; Energy-efficient eHealth architectures; Big data analysis for eHealth; Optical fiber sensors for rehabilitation; Optical fiber immunosensors; Biomarker detection; Low-cost, miniaturized, selective, and multiparameter optical fiber devices; Innovative materials for medical applications; Advanced signal processing techniques; Applications including but not limited to: dentistry, surgery, robotics, medical diagnostics and therapy, pharmaceutical research, and cardiovascular and chronic diseases. Dr. Nélia J. Alberto Dr. Maria de Fátima Domingues Dr. Paulo Antunes Guest Editors
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